John Mahoney, best known for playing Martin Crane on 11 seasons of Frasier, has died in Chicago at the age of 77.
Mahoney's longtime manager, Paul Martino, said the actor died on Sunday while in hospice care.
Mahoney played the father of Kelsey Grammer and David Hyde Pierce's characters during the show's run on NBC from 1993 to 2004. He won a SAG Award and received two Emmy and two Golden Globe nominations for his portrayal.
From 2011 to 2014, he had a recurring role on Hot in Cleveland as Roy, the love interest of Betty White's character, Elka.
Mahoney worked in film for more than 35 years, appearing in classics like The American President and Say Anything, along with voicing animated characters in the Antz and Atlantis films.
He came to the U.S. at age 19 and taught English at Western Illinois University before entering into the entertainment industry in 1977.
Mahoney never married and didn't have any children.